Over-the-counter options for osteoarthritis joint pain

RosaLipidTM  is a natural extract derived from wild rosehip berries, used for the treatment of osteoarthritis.
This natural plant extract offers people a viable alternative to harsh pharmaceutical drugs and supplements like glucosamine and chondroitin which simply don’t work.
The main ingredient in this extract is a galactolipid known as GOPO which is building a pedigree of good clinical research that proves it’s efficacy. 

Are you looking for a new ingredient for your osteoarthritis product? Need a sample to get on with some R&D work?
Drop your email below and we’ll reach out to you. We’d love the opportunity to connect.

Nature’s tonic for inflammation

Pharmacological Action

Rosehip displays a wide range of therapeutic effects. This plant-based superfood has been the subject of over 30 clinical studies and is rapidly gaining a global reputation as a natural arthritis antidote. Rosehip’s unique therapeutic activities are attributed to a complex range of phytochemicals, including a particular galactolipid, commonly known as GOPO.

The inflammatory pathway in osteoarthritis

Osteoarthritis occurs in joints where the cartilage covering the surface of bone begins to breakdown. This occurs due to genetic factors as well as trauma to the joint or simple wear and tear. As the cartilage breaks down, small particles are released into the synovial fluid in the joint. The body attempts to address this by initiating an inflammatory response. White blood cells in the synovial fluid ingest the debris and produce chemical signalling molecules called cytokines. This process is often referred to as a ‘cytokine storm’. These cytokines cause more inflammation and so begins a vicious cycle, which leads to further erosion of the joint’s cartilage.

GOPO, the active ingredient in Rosehip, acts as a calmative agent by inhibiting a number of the above processes. Firstly, GOPO reduces the production of white blood cells which cause further cell injury (neutrophil chemotaxis).

Secondly, it slows the production of the inflammatory mediators called cytokines. It was further demonstrated that GOPO protects cartilage by influencing the way genes are expressed. GOPO promotes the regeneration of cartilage cells and the manufacture of an essential component of cartilage, called collagen. Overall GOPO acts to soothe the inflammatory cascade, significantly reducing inflammation and pain.

GOPO has displayed great success in treating both osteoarthritis and rheumatoid arthritis. Treatment with GOPO produces a reduction in pain, an increase in joint mobility, relief of swelling, improvements in mobility and improved sleep for arthritis patients. It may also be beneficial in the treatment of inflammatory bowel disease, gout and sciatica.

Antioxidant

Rosehip is often referred to as a ‘functional food’ because it is rich in Vitamin C and polyphenolic compounds which defend tissues against harmful free radicals. Indeed, fresh rosehip contains more Vitamin C than citrus fruit. Rosehip’s antioxidant activity protects the body by neutralizing potentially damaging oxidising agents. It also enhances the action of specialised antioxidant enzymes. Oxidative stress is implicated in many chronic diseases including heart disease, cancer, diabetes, stroke and neurodegeneration.

Anti-diabetic, lipid lowering and anti-obesogenic activity

Investigations in animals have demonstrated that rosehip extracts lower blood sugar levels, leading researchers to examine its efficacy as a treatment for diabetes. Furthermore, rosehip extracts have been shown to prevent weight gain and reduce body fat percentages in human trials. Daily consumption of rosehip powder can significantly reduce cardiovascular risk in obese people through lowering of blood pressure and cholesterol levels.

Three-Way Effect

RosaLipidTM has been shown to have a three-way effect.

afrigetics-botanicals-rosalipid-rosehip-extract-three-way-effect

Anti-inflammatory

The efficacy of the GOPO extract as a natural anti-inflammatory has been well researched. This extract has been the subject of a number of double blind, placebo controlled trials involving hundreds of osteoarthritis sufferers (Christensen et al, 2008). A meta-analysis of data from three prominent studies confirmed that GOPO offers “significant and robust joint pain relief, enabling a reduction in the consumption of rescue medications” (NICE, 2014).

Pain Relief

A meta-analysis of data from three prominent studies confirmed that GOPO offers “significant and robust joint pain relief, enabling a reduction in the consumption of rescue medications” (NICE, 2014).

Reduced Medication

Winther’s 2013 clinical trial focussed on patients with osteoarthritis of the dominant hand. 90% of the subgroup taking rosehip containing GOPO reported reductions of pain in the hand while on active treatment. Active treatment also resulted in a 33% reduction in the consumption of rescue medication. Symptom reduction was still present 3 weeks after a switch to the placebo, further evidencing the long duration of GOPO’s action (Winther et al., 2013).

afrigetics-botanicals-rosalipid-rosehip-extract-products-sample
RosaLipid TM Sample

Sample

Product Description

RosaLipidTM  is the powdered fruit and lipid components of the whole Rosehip combined into a valuable medicinal complex. We understand that nature packages nutrients in their perfect ratio and seeks to mimic that perfect balance in preparing the RosaLipidTM 4:1 complex. In this way bioavailablity is maximised and the complex delivers its medicinal phytochemicals in their most active form.

Active Ingredient

Sterilisation

Packaging Description

Pack Size

Request a sample and/or brochure

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RosaLipid TM 

Powder Extract

Product Description

RosaLipidTM  is the powdered fruit and lipid components of the whole Rosehip combined into a valuable medicinal complex. We understand that nature packages nutrients in their perfect ratio and seeks to mimic that perfect balance in preparing the RosaLipidTM 4:1 complex. In this way bioavailablity is maximised and the complex delivers its medicinal phytochemicals in their most active form.

Active Ingredient

Sterilisation

Packaging Description

Pack Size

Request a sample and/or brochure

afrigetics-botanicals-rosalipid-rosehip-extract-download-brochure
RosaLipid TM

Download Brochure

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