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RosaLipidTM is our flagship new botanical extract for the natural treatment of Osteoporosis-Arthritis.

Our new product, RosaLipidTM, derived from wild-crafted rosehip berries, is an exciting new option for natural osteoarthritis treatment.

This extract is rich in galactolipids, one in particular referred to as GOPO, which has shown to be effective for pain relief, increased joint mobility and as an anti-inflammatory.

In epidemiology, half of the world’s population aged 65 years or older has OA, which is the most prevalent disorder of articulating joints in humans.

RosaLipidTM which is rich in the galactolipid GOPO, is a natural and effective ingredient that has the power to make a real difference to the quality of life of OA suffered.

You can read more about this remarkable healing plant below.

Over-the-counter options for osteoarthritis joint pain

RosaLipidTM  is the powdered fruit and lipid components of the whole Rosehip combined into a valuable medicinal complex. We understand that nature packages nutrients in their perfect ratio and seeks to mimic that perfect balance in preparing the RosaLipidTM 4:1 complex. In this way bioavailablity is maximised and the complex delivers its medicinal phytochemicals in their most active form.

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Mountain Origins

The Zulu people named the 300-kilometre section of mountain range bordering KwaZulu-Natal and the mountain Kingdom of Lesotho ‘uKhahlamba, meaning “Barrier of Spears”. The early Dutch settlers called the rugged peaks the Drakensberge or ‘Dragon Mountains’. Nowadays, this breath-taking wilderness is referred to by locals simply as the ‘Berg’. It is here, between dramatic mountain peaks, the thorny creeper, Rosa canina, reveals tremendous healing properties. 

The pretty summer wildflower is more commonly known to occupy hedgerows and woodlands in Europe. Its fragrant pale pink petals are used as a perfume. The bright red fleshy fruits were traditionally harvested and boiled down for rosehip syrup, herbal teas and marmalade. In addition to its long history of food use in Europe, an oil pressed from the seeds was favoured by ancient Egyptians for its remarkable healing properties. Rosehip is one of the best vegetable sources of omega 3, 6 and retinoic acid, making it prized for its ability to repair damaged skin tissue.

Extracts of the rosehip seeds and fruit harbour phytochemicals now universally praised for their tremendous medicinal properties. Afrigetics now package the essential inflammation fighting properties in their flagship extract RosaLipids™ 4:1.

Indigenous to Europe, Northwest Africa and Western Asia, the Dog Rose as it is also known, was introduced to South Africa by British explorers as a fodder for horses in the 19th century. It is believed that nutritious feedstock, imported from South America, held millions of rosehip fruit and seeds. These valuable horse rations allowed the explorers to travel extensively through the Drakensburg Mountains and offered osteoarthritic relief for the animals. Passage though the horse’s digestive system activated germination of the seeds. The woody creeper grew prolifically along the banks of the major rivers and the water courses in turn carried and deposited the seeds. Rosa canina quickly flourished across the moist valleys and disturbed soil of the Lesotho highlands. The cold, dry air and high altitude particularly suited the growth of R. canina and it quickly invaded the remote land-locked kingdom.

Nature’s tonic for inflammation

Ethical Source

Lesotho is a very poor country with about 40% of the population living below the international poverty line. Lesotho is declared a high altitude desert leaving rural people little in the way of a sustainable income, especially in the winter months. Rosehips are hand-picked in winter, mainly by women, providing the local communities with valuable and sustainable economic opportunities.

The rosehips are certified organic and accredited by the “FairWild Foundation”. BMO liaise with local community councils in Lesotho to ensure that the rosehips are collected sustainably, that the biodiversity of the region is preserved and a just price is paid to local harvesters. Dane Vaughan Poulsen comments; “everyone involved in value chain receives fair value, harvesters are paid fairly and given an opportunity to enjoy reasonable living conditions”. It’s vital to BMO that other potentially vulnerable plant species in the local ecosystems are protected.  BMO’s RosaLipid™ 4:1 is also Rainforest Alliance certified, ensuring the ecological integrity is maintained and local forests are not destroyed in the harvesting of drying fuel.

In addition to supplementing their income, and under the stipulations of the Nagoya Protocol, local collectors and land owners profit from a benefit sharing agreement where a rand value of their harvest is paid into a government controlled ‘Bioprospecting Trust Fund’ for distribution within the community.

Afrigetics are proud to partner with Bright Mountain Oil, a company which exhibits exceptional integrity and shares a vision which places Africa’s people and plants before profit. “Africa is traditionally a continent in which rural people are high jacked by big corporations and value is channelled to the wealthiest,” says Poulsen. “We want to create a different economy,” he explains “where we provide the infrastructure for local communities to utilise their own creativity and skills to unlock the value at their feet”.

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Pharmacological Action

Rosehip displays a wide range of therapeutic effects. This plant-based superfood has been the subject of over 30 clinical studies and is rapidly gaining a global reputation as a natural arthritis antidote. Rosehip’s unique therapeutic activities are attributed to a complex range of phytochemicals, including a particular galactolipid, commonly known as GOPO.

The inflammatory pathway in osteoarthritis

Osteoarthritis occurs in joints where the cartilage covering the surface of bone begins to breakdown. This occurs due to genetic factors as well as trauma to the joint or simple wear and tear. As the cartilage breaks down, small particles are released into the synovial fluid in the joint. The body attempts to address this by initiating an inflammatory response. White blood cells in the synovial fluid ingest the debris and produce chemical signalling molecules called cytokines. This process is often referred to as a ‘cytokine storm’. These cytokines cause more inflammation and so begins a vicious cycle, which leads to further erosion of the joint’s cartilage.

GOPO, the active ingredient in Rosehip, acts as a calmative agent by inhibiting a number of the above processes. Firstly, GOPO reduces the production of white blood cells which cause further cell injury (neutrophil chemotaxis).

Secondly, it slows the production of the inflammatory mediators called cytokines. It was further demonstrated that GOPO protects cartilage by influencing the way genes are expressed. GOPO promotes the regeneration of cartilage cells and the manufacture of an essential component of cartilage, called collagen. Overall GOPO acts to soothe the inflammatory cascade, significantly reducing inflammation and pain.

GOPO has displayed great success in treating both osteoarthritis and rheumatoid arthritis. Treatment with GOPO produces a reduction in pain, an increase in joint mobility, relief of swelling, improvements in mobility and improved sleep for arthritis patients. It may also be beneficial in the treatment of inflammatory bowel disease, gout and sciatica.

Antioxidant

Rosehip is often referred to as a ‘functional food’ because it is rich in Vitamin C and polyphenolic compounds which defend tissues against harmful free radicals. Indeed, fresh rosehip contains more Vitamin C than citrus fruit. Rosehip’s antioxidant activity protects the body by neutralizing potentially damaging oxidising agents. It also enhances the action of specialised antioxidant enzymes. Oxidative stress is implicated in many chronic diseases including heart disease, cancer, diabetes, stroke and neurodegeneration.

Anti-diabetic, lipid lowering and anti-obesogenic activity

Investigations in animals have demonstrated that rosehip extracts lower blood sugar levels, leading researchers to examine its efficacy as a treatment for diabetes. Furthermore, rosehip extracts have been shown to prevent weight gain and reduce body fat percentages in human trials. Daily consumption of rosehip powder can significantly reduce cardiovascular risk in obese people through lowering of blood pressure and cholesterol levels.

Three-Way Effect

RosaLipidTM has been shown to have a three-way effect.

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Anti-inflammatory

The efficacy of the GOPO extract as a natural anti-inflammatory has been well researched. This extract has been the subject of a number of double blind, placebo controlled trials involving hundreds of osteoarthritis sufferers (Christensen et al, 2008). A meta-analysis of data from three prominent studies confirmed that GOPO offers “significant and robust joint pain relief, enabling a reduction in the consumption of rescue medications” (NICE, 2014).

Pain Relief

A meta-analysis of data from three prominent studies confirmed that GOPO offers “significant and robust joint pain relief, enabling a reduction in the consumption of rescue medications” (NICE, 2014).

Reduced Medication

Winther’s 2013 clinical trial focussed on patients with osteoarthritis of the dominant hand. 90% of the subgroup taking rosehip containing GOPO reported reductions of pain in the hand while on active treatment. Active treatment also resulted in a 33% reduction in the consumption of rescue medication. Symptom reduction was still present 3 weeks after a switch to the placebo, further evidencing the long duration of GOPO’s action (Winther et al., 2013).

Galactolipids (GOPO)

Afrigetics’ complex is derived from the seeds and fruits of Rosa canina, the wild briar rose. This superfood supplement contains a vast array of nutrients, including a range of essential fatty acids. The star of this lipid array is a phenomenal natural anti-inflammatory and powerful antioxidant. This compound is a galactolipid is known scientifically as 1,2-di-O-alpha-linolenoyl-3-O-beta-D-galactopyranosyl-sn-glycerol or GOPO for short.

Galactolipids are a class of biomolecules found throughout the plant kingdom. This group of chemical compounds consist of a sugar group bonded to a lipid molecule. Galactolipids are isolated from edible plants and are an important building blocks of cell membranes. The active galactolipid in Rosehip, GOPO, has been shown in clinical trials to be an excellent natural anti-inflammatory. GOPO has also been shown to arrest the disintegration of cartilage in arthritis patients.

The body’s natural response to inflammation is to ‘clean up’ swollen joints. The immune system launches an assault by white blood cells at the site of inflammation.

White blood cells are the body’s defence against invading bacteria. This attraction process is known as ‘chemotaxis’. RosaLipids ™4:1  bioactive ingredient, GOPO, acts by interfering with this process. This results in fewer white blood cells accumulating at the site of swelling, thereby reducing discomfort, inflammation and pain.

Furthermore, GOPO is known to have immense ‘chondroprotective capacity’. In joints effected by osteoarthritis, white blood cells undergo an ‘oxidative burst’ response. The cells produce vast quantities of toxic free radicals which wear down cartilage by attacking the vital proteins which keep cartilage stable.

Eroded cartilage exacerbates pain, discomfort and swelling. GOPO’s antioxidant effect is due to its influence on gene expression. GOPO stimulates the activity of antioxidant enzymes such as superoxide dismutase and catalase, which deactivate free radicals. GOPO also enhances the expression of genes which build collagen at joints and it actively restores key cartilage building cells, called chondrocytes.

It is now known that GOPO does not act alone, but in concert with many other phytochemicals in the rosehip complex. These other bioactive ingredients enhance the biological effect of RosaLipids ™4:1  GOPO, helping to break the vicious cycle of joint inflammation, alleviating pain, restoring quality of life and protecting mobility.

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Read more about the research done on RosaLipid

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Rosa Canina (Rosehip)

Sample

Product Description

RosaLipidTM  is the powdered fruit and lipid components of the whole Rosehip combined into a valuable medicinal complex. We understand that nature packages nutrients in their perfect ratio and seeks to mimic that perfect balance in preparing the RosaLipidTM 4:1 complex. In this way bioavailablity is maximised and the complex delivers its medicinal phytochemicals in their most active form.

Active Ingredient

Sterilisation

Packaging Description

Pack Size

Request a sample and/or brochure

afrigetics-botanicals-rosalipid-rosehip-extract-products
Rosa Canina (Rosehip)

Powder Extract

Product Description

RosaLipidTM  is the powdered fruit and lipid components of the whole Rosehip combined into a valuable medicinal complex. We understand that nature packages nutrients in their perfect ratio and seeks to mimic that perfect balance in preparing the RosaLipidTM 4:1 complex. In this way bioavailablity is maximised and the complex delivers its medicinal phytochemicals in their most active form.

Active Ingredient

Sterilisation

Packaging Description

Pack Size

Request a sample and/or brochure

afrigetics-botanicals-rosalipid-rosehip-extract-download-brochure
RosaLipid TM

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